Differential diagnostics of bronchial allergy and chronic obstructive lung disease

19 June 2011
Written by Grinshtein Yu.I., Shestovitskiy V.A., Maksimova A.V.

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The authors have studied cytological peculiarities and processes of free radical oxidation by chemiluminescent indices of phagocytizing inflammatory cells in breathing passages of patients suffering from bronchial allergy and chronic obstructive lung disease. Having examined 128 patients, they proved firm differences, which may be used as additional criteria for differential diagnostics of these diseases. Based on study materials, they received a patent of Russian Federation for invention Nr. 2262095 dated 10.10.2005.

Links to authors:

Yu.I. Grinshtein, V.A. Shestovitskiy, A.V. Maksimova
Krasnoyarsk State Medical University named after Prof. V.F. VoynoYasenetskiy (1 Partizana Zheleznyaka Street, Krasnoyarsk 660022), Nr. 20 Municipal Clinical Hospital named after I.S. Berzon (12 Instrumental Street, Krasnoyarsk 660022 Russian Federation)

  1. The global strategy for the treatment and prevention of asthma
    (GINA). M.: Atmosfera, 2007. 160 p.
    2. The global strategy for the diagnosis, treatment and prevention
    of chronic obstructive pulmonary disease / ed. A.G. Chuchalina.
    M.: Atmosfera, 2007. 96 p.
    3. Daniljak I.G., Kogan A.H., Bolevich S. et.al. The generation of
    reactive oxygen species by alveolar macrophages in patients with
    bronchial asthma, Problemy tuberkuleza. 1993. no. 4. P. 55–58.
    4. Clinical recomendations: asthma / ed. A.G. Chuchalina. M.:
    Atmosfera, 2008. 224 p.
    5. Maksimova A.V., Grinshtejn Ju.I., Shestovickij V.A. The method
    of differential diagnosis of chronic obstructive pulmonary disease.
    Patent no. 2262095 at 10.10.2005.
    6. Prozorova V.K., Karlov A. I., Arhipov V.V. How was the approach
    to the treatment of asthma in recent years, Farmateka. 2009. no.
    5. P. 39–42.
    7. The standards for the diagnosis and treatment of patients with
    chronic obstructive pulmonary disease / ed. A.G. Chuchalina.
    M.: Atmosfera, 2005. 96 p.
    8. Tatarskij A.R. Diagnosis, differential diagnosis and treatment of
    bronchial obstruction syndrome: the place of combination pills
    β/2‑agonistov and inhaled corticosteroids, Pulmonologija. 2011.
    No. 1. P. 89–98.
    9. Shestovickij V.A., Grinshtejn Ju.I. Severe asthma. Krasnojarsk:
    Klaretianum, 2003. 148 p.
    10. Shmelev E. I. A combination of asthma and chronic obstructive
    pulmonary disease, Consilium medicum. 2004. Vol. 6, No. 10. P.
    11. Bateman E.D., Boushey H., Bousquet J. et al. Stability of asthma
    control with regular treatment: an analysis of the Gaining Optimal
    Asthma control (GOAL) study, Allergy. 2008. Vol. 63. Р. 932–938.
    12. Global strategy for the diagnosis, management and prevention of
    chronic obstructive pulmonary disease. NHLBI/WHO workshop
    report. Bethesda, National Heart, Lung and Blood Institute, up‑
    date 2006 // URL: www.goldcopd.com (date15.05.2010).
    13. Rabe K.F., Atienza T., Magyar P. et al. Effect of budesonide in
    combination with formoterol for reliever therapy in asthma ex‑
    acerbations: a randomised controlled, double‑blind study, Lancet.
    2006. Vol. 368. Р. 744–753.


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