Effect of sodium alginate on spontaneous and induced cytokine production by peripheral blood mononuclear cells of healthy donors in vitro

25 March 2011
Written by Sergeeva N.V., Bogdanovich L.N., Khotimchenko Yu.S.

  UDK: 577.112:612.017.1:577.114 | Pages: 35–37 | Read full textDownload PDF 


The paper describes effects of sodium alginate on the spontaneous and induced cytokine production (interleukin 2 and 6 and tumour necrosis factor‑α) by peripheral blood mononuclear cells of 16 healthy donors. As reported, the sodium alginate appears to have considerable concentration‑dependent cytokine‑induced action on interleukin 2 and weak action on interleukin 6 and tumour necrosis factor‑α.

Links to authors:

N.V. Sergeeva, L.N. Bogdanovich
Medical Association of FEB RAS (95 Kirova St. Vladivostok 690022 Russian Federation)
Yu.S. Khotimchenko
Institute of Marine Biology (17 Palchevskogo St. Vladivostok 690041 Russian Federation)

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