Рrebiotic properties of polysаcсharides from brown seaweed Fucus evanescens and perspectives for clinical using

27 May 2011
Written by Kuznetsova T.A., Zaporozhetz T.S., Besednova N.N., Makarenkova I.D., Timchenko N.F., Zvyagintseva T.N., Shevchenko N.M., Мandrakova N.V., Mеlnikov V.G.

  UDK: 615.322:577.114:582.272 | Pages: 37–40 | Read full textDownload PDF 


The prebiotic potential of polysаcсharides (PS) from brown seaweed Fucus evanescens were studied in vitro and in vivoexperiments. We established that fucoidan and alginic acid stimulate the growth and accumulation of bifidobacteria biomass, i.e. these PS possess prebiotic activity. We revealed the restoration of quantitative and qualitative composition of intestinal microflora (increasing content of bifido‑ and laсtobacteria, typical Escherichia coli and reduction of opportunistic microflora) in mice with antibiotic‑induced dysbiosis, treated with fermented by bifidobacteria and enriched with these PS milk. The presence of prebiotic activity opens the perspectives for inclusion of this PS to products of functional food, dietary supplements and sinbiotic preparations for the correction of human’s microbiota disorders.

Links to authors:

T.A. Kuznetsova, T.S. Zaporozhetz, N.N. Besednova, I.D. Makarenkova, N.F. Timchenko1
Research Institute of Epidemiology and Microbiology, Siberian Branch of Russian Academy of Medical Sciences (1 Selskaya St. Vladivostok 690087 Russia)
T.N. Zvyagintseva, N.M. Shevchenko
Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Science (159 100 Ann. of Vladivostok Av. Vladivostok 690022 Russia)
N.V. Мandrakova
Vladivostok State Medical University (2 Ostryakova Av. Vladivostok 690950 Russia)
V.G. Mеlnikov
International Science and Technology Center (20 box 32–34 Krasnoproletarskaya St. Moscow 127473 Russia)

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