Antiviral effect of brown algae-derived sulphated polysaccharides in case of experimental tick-borne encephalitis: tying structure and function

23 March 2011
Written by Makarenkova I.D., Leonova G.N., Maystrovskaya O.S., Zvyagintseva T.N., Imbs T.I., Ermakova S.P., Besednova N.N.

  UDK: 616.831‑002‑085.281.8:577.144:582.272 | Pages: 44–46 | Read full textDownload PDF 


The authors have conducted comparable studies of antiviral effect of sulphated polysac‑charides – fucoidans derived from brown algae Laminaria japonica, Laminaria cichorioides, Fucus evanescens and Costaria costata on the SPEV biocytoculture infected with tick‑borne encephalitis virus. As reported, the fucoidans are known for virucidal effect against the high pathogenic strain of tick‑borne encephalitis virus and capacity of suppressing virus adsorption and replication at early disease stages in vitro.

Links to authors:

I.D. Makarenkova, G.N. Leonova, O.S. Maystrovskaya, N.N. Besednova
Research Institute of Epidemiology and Microbiology of the Siberian Brach of Russian Academy of Medical Sciences (1 Selskaya St. Vladivostok 690087 Russian Federation)
T.N. Zvyagintseva, T.I. Imbs, S.P. Ermakova
Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of Russian Academy of Sciences (159 100 Year Anniversary of Vladivostok Av. Vladivostok 690022 Russian Federation)

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