Biocompatible matrix implants from natural and synthetic polymers as promising products intended for treatment of degenerative and post-injury diseases of central nervous system

10 May 2011
Written by Khotimchenko Yu.S., Scheblyikina A.V., Kumeiko V.V.

  UDK: 616.831‑089.819.843:677.021.122.6 | Pages: 54-60 | Read full text  | Download PDF 


The authors provide an overview of modern studies and developments in the field of biocompatible implantable materials designed for treating degenerative and post‑injury pathologies of central nervous system. As reported, the critical analysis of materials and their components derived from natural and synthetic polymers allows concluding that their application as matrix implants can make it possible to recover the integrity of injured brain, adjust supportive and trophic functions, and induce reparative processes due to inner and implantable cell sources. The up‑to‑date state of biomedical material sciences and tissue engineering for the needs of neurotransplantology is characterised as analysis of capability of materials to imitate the structure and functions of natural extracellular matrix, inducing neurogenesis and recovering conductive functions of the nervous system, and capabilities of materials to be exposed to controlled biodegradation with subsequent substitution with tissue structures.

Links to authors:

Yu.S. Khotimchenko, A.V. Scheblyikina, V.V. Kumeiko
A.V. Zhirmunsky Institute of Marine Biology (17 Palchevskogo St. Vladivostok 690041 Russia),
Yu.S. Khotimchenko, V.V. Kumeiko
Far Eastern Federal University (8 Sukhanova St. Vladivostok 690950 Russian Federation)

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