Stem cells of neuronal origin in mammal’s brain

23 March 2011
Written by Okhotin V.E., Revischin A.V., Pavlova G.V.

  UDK: 611.018.82:576.3 | Pages: 60-65 | Read full textDownload PDF 


New knowledge about stem cells that make it possible to in a new light interpret the functioning of nervous tissue in health and disease has been obtained during the last fifteen years. As reported, the proliferating stem cells in a definitive brain under certain conditions can be involved in reparative regeneration by substituting dead elements. The authors identify genome mechanisms of regulating proliferation and differentiation of stem cells and point out their role in producing malignant tumours and tropism of these cells to the tumours. These data open new opportunities for studying brain functioning and development. The neutral stem cells can be used to develop new technologies, treat neurogenerative and oncological diseases of brain.

Links to authors:

V.E. Okhotin, G.V. Pavlova
Institute of Gene Biology, RAS (34/5 Vavilova St. Moscow 119334 Russia),
A.V. Revischin
A.N. Severtsov Institute of Ecology and Evolution (33 Leninskiy Av. Moscow 119071 Russian Federation)

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