Features of arterial hypertension and smoking‑related cerebrovascular dysfunction

Written by Nevzorova V.A., Zaharchuk N.V., Agafonova I.G., Sarafanova N.S.

  Индекс УДК: 616.13‑004.6‑06: 616.12‑008.331.1: 613.84 | Страницы: 9-16 | Полный текст статьи. PDF файл | Открыть PDF 


The authors review the literature data and in‑house researches on arterial hypertension and smoking‑related changes in cerebral vessels clinically and in experiment, and provide the data from transcranial Doppler ultrasound examination, duplex scanning and magnetic‑resonance imaging of cerebral vascular bed. As shown, the arterial hypertension and smoking‑related cases were characterised by decreased linear blood flow velocity, increased vascular resistance index and more evident cerebral atherosclerosis. The smoking intensity directly correlated with the prevalence of atherosclerotic plaques, including hemodynamically significant stenosis. The authors have identified evident cerebral vasomotor disorders, such as the loss of endothelium‑dependent vasodilatation and increase in vasoconstrictive effects.

Ссылки на авторов:

V.A. Nevzorova, N.V. Zaharchuk
Pacific State Medical University (2 Ostryakova Av. Vladivostok 690950 Russian Federation)
I.G. Agafonova
Pacific Institute of Bioorganic Chemistry (159 Vladivostok 100-year Anniversary Av. Vladivostok 690022 Russian Federation)
N.S. Sarafanova
Naval Clinical Hospital of the Pacific Fleet (4 Ivanovskaya St. Vladivostok 690001 Russian Federation)

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