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Osteoarthritis and microcrystalline stress phenomenon

Written by Kabalyk M.A., Dubikov A.I., Petrikeeva T.Y., Karabtsov A.A., Kuzmin I.I., Cherepovskiy A.V

  UDK: 616.718.4-02:577.118: 616.72-018.3 | Pages: 70–74 | Full text PDF | Open PDF 

Annotation:

Background. The importance of the phenomenon of mineralization of cartilage due to osteoarthritis (OA) proved by an evidence of factors contributing to this process. The object of this study is to determine the clinical and pathogenetic significance of microcrystallisation of the articular cartilage caused by OA.
Methods. The study embraced 110 persons operated on coxarthrosis from II to IV grades by (osteoarthritis grading system of) Kellgren and Lawrence and 50 persons undergone hip replacement after a coxal fracture. Methods of X-ray structure analysis used for examining tangential sections of a resected capitular of the femoral bone cartilage.
Results. A phenomenon of mineralization of cartilage due to OA amounts 72.7 % of records, in C group – 16 %. The prevalence of microcrystallisation increased in accordance with the progression of radiographic symptoms of disease. Despite women have the greater predisposition to OA, mineralization of cartilage has an even frequency for both sexes.
Conclusions. High prevalence of mineralization of articular cartilage due to OA compared with a comparable C group enables to consider the microcrystalline deposition to be an important attendant factor of the pathogenesis of this disease.

Links to authors:

M.A. Kabalyk1, A.I. Dubikov1, T.Y. Petrikeeva1, A.A. Karabtsov2, I.I. Kuzmin1, A.V. Cherepovskiy1
1 Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690950 Russian Federation)
2 Far East Geological Institute of the Russian Academy of Sciences Far East Branch (159, 100th years of Vladivostok Ave. Vladivostok 690022 Russian Federation)

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