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Substantiation of the choice of the medicamentous treating‑and‑prophylactic complex at mild parodontitis

Written by Mihal’chenko V.F., Yakovlev A.T., Patrusheva M.S.

  UDK: 616.314.17-008.1-084 | Pages: 42–45 | Full text PDF | Open PDF 

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Background. Now in the pharmaceutical market the considerable quantity of medicamentous complexes for treatment and preventive maintenance of parodontal diseases is presented. The research objective – comparison of the efficiency of treatment and cost at use of the stomatologic treatment-and-prophylactic complexes “Asepta”, “Vivax” and “Wood balm”.
Methods. 106 patients of 20–35 years old with mild chronic generalized parodontitis depending on the used treatment-and-prophylactic complex have been divided into three groups. Treatment duration – 14 days. Control examinations were done in 7, 14, 60, 120 and 180 days after the treatment beginning. In all cases the index estimation of the parodont state and the estimation of the alkaline phosphatase, lactate dehydrohenase and phosphor lipase А2 activity levels in the gingival liquid were done. Calculated the ratio of expenses and efficiency.
Results. In 7 days after the beginning of treatment at patients of all groups clinical improvement was shown. Level of hygiene of the oral cavity without authentic distinctions between groups has considerably raised and remained at good level till the end of the follow-up period. The most expressed positive dynamics and peak of treatment efficiency were noted at the patients using “Asepta”. Initial hyperactivity of enzymes was normalized during the follow- up period but was similar to control only at “Asepta” group. The maximum expenses for efficiency unit were 24.85 roubles at “Vivax” use. At “Asepta” and “Wood balm” series use this index was 4.70 and 4.10 roubles, respectively.
Conclusions. The use of medicamentous complexes “Asepta”, “Vivax” and “Wood balm” promote the disappearance of the parodontitis signs. The use of such series as “Asepta” helps to achieve faster and long anti-inflammatory effect. The use of this complex expediently also from the economic point of view.

Links to authors:

V.F. Mihal’chenko1, A.T. Yakovlev2, M.S. Patrusheva1
1 Volgograd State Medical University (1 Bortsov square Volgograd 400141 Russian Federation),
2 Volgograd Research Anti-plague Institute (7 Golubinskaya St. Volgograd 400131 Russian Federation)


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