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Cellular and post-genomic approaches to the treatment of lioblastoma multiforme

Written by Bryukhovetskiy I.S.

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Glioblastoma multiforme, one of the most aggressive human brain tumor. Most current treatments are not effective, the median survival time of 12–14 months. One of the leading causes of treatment resistance is associated with tumor stem cells. The analysis of modern approaches to the creation of biomedical drugs effects on tumor stem cells glioblastoma multiforme on the achievements of modern cellular and post-genomic technologies. Proposed the idea of a combination of methods of targeted therapy with technology regulation of the key functions of tumor stem cells cellular systems with remodel proteome.

Links to authors:

I.S. Bryukhovetskiy
School of Biomedicine, Far Eastern Federal University (8 Sukhanova St. Vladivostok 690950 Russian Federation)


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