The spatial organization of gas-transmitral neurons in the brain

Written by Startseva М.S., Kotsuba А.Е., Chertok V.М.

  UDK: 611.818/611.82:612.127 | Pages: 39–43 | Full text PDF | Open PDF 


Background. The research objective is an analysis of spatial relations of gas-transmitral neurons in the caudal portion of the brain stem of rats. Methods. The study was performed on 12 adult male rats Wistar weighing 200–240g. Immunopositive neurons groups were studied with immunohistochemical methods for nitric oxide synthase, heme oxygen-ase-2, and cystathionine β-synthase in the projection of the nucleus of the solitary tract, small-cell and gi-ant cell reticular nucleus. Results. Dimensions, share and concentration of NO-, CO- and H2Sof immunopositive neurons as well as their distribution in each of the investigated nuclei are exceptionally unique. Most of these cells were located in close proximity to each other, forming more or less distinct clusters of neurons of different me-diator specificity. Conclusions. In the organization of vasomotor nuclei there are structural conditions for cooperation NO-, CO- and H2S- of immunopositive neurons and their integration into functional nerve centers of the brain that enhances the management of complex processes in the body.

Links to authors:

М.S. Startseva, А.Е. Kotsuba, V.М. Chertok
Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690950 Russian Federation)

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