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Influence of bone density in the thromboembolic complications after total knee endoprosthesis replacement

Written by Vahrushev N.А., Eliseeva Е.V., Goncharova R.K.

  UDK: 616-089.819.843-06:615.151.5-005.5/.7:611.018.4 | Pages: 83–85 | Full text PDF | Open PDF 

Annotation:

Background. Nowadays there is no data on the effect of bone density on the incidence of venous thrombo-embolism after total knee endoprosthesis replacement. Methods. The study involved 80 patients who underwent total knee endoprosthesis replacement. Condi-tion of bone mineral density was studied by dual energy x-ray absorptiometry of the proximal femur and lumbar spine. Given the importance of T-score patients were divided into two groups: the 1st – 40 patients with T-score not lower –2,5 SD, 2nd – 40 patients with T-score of less than –2,5 SD. Veins condition of the lower limbs was assessed using Doppler ultrasound. D-dimer levels were used as a laboratory marker of thrombus. Results. There was a significant increase in the concentration of D-dimer in the 7th postoperative day, more pronounced in the 2nd group. The differences between the values of the group maintained during 6 months. 6 months later, after surgery venous thrombosis of the lower limbs was diagnosed in 2.5 % of patients in group 1 and 7.5 % of patients in group 2. Conclusions. An interconnection was detected between the increased incidence of venous thrombosis and decreased bone mineral density in patients with osteoarthritis of the knee joint after total endoprosthesis replacement. There is a necessity of further studying of the characteristics of thrombosis in patients with osteoporosis after operations on the joints.

Links to authors:

N.А. Vahrushev, Е.V. Eliseeva, R.K. Goncharova
Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690950 Russian Federation)


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