Morphofunctional parameters of retinal ganglion cells and their features in the openangle glaucoma

Written by Matveeva N.Y., Kalinichenko S.G., Edranov S.S.

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The review summarizes the literature data and author’s own researches data of morphofunctional typology of retinal ganglion cells (GC) of a human and animals. GS are effector glutamatergic neurons which differ in size and shape of the body; in axon diameter; stratification of dendritic arbor and density branching. Due to various dendritic arborization it is possible to separate diffuse, stratified, and biplexiform cells. GC, being a main aim of a cytological impact of glutamate and nitrogen oxide, are involved in a pathogenesis of an openangle glaucoma. In this case the apoptosis of neurons is supposed to relate to the morphological type of GC and the activating recipient of their synaptic microenvironment.

Links to authors:

N.Y. Matveeva, S.G. Kalinichenko, S.S. Edranov
Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690950 Russian Federation)

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