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Clinical-functional features of cardio-vascular complications in chronic glomerulonephritis

Written by Murkamilov I.T., Kaliev R.R., Kaliev K.R., Aitbaev K.A.

  UDK: 616.1-06:616.611-002-036.12 | Pages: 41–46 | Full text PDF | Open PDF 

Annotation:

Background. Studies in experimental and clinical nephrology found mechanisms of development, and substantiated some ways to treat diseases of the cardiovascular system in anemia caused by chronic kidney disease. Nevertheless, the number of studies dedicated to the defeat of the cardiovascular system in patients with chronic glomerulonephritis (CGN) at a predialysis stage is still small, and the results are inconsistent.
Methods. The study included 631 patients aged 16 to 65 years, with CGN in the predialysis stage of the disease. According to various aspects of the defeat of the cardiovascular system it was compared clinical and laboratory surveillance data of patients with and without anemia.
Results. Among patients with CGN and anemia were significantly more frequent coronary heart disease, supraventricular and ventricular arrhythmias, and heart failure than in patients suffering from CGN without anemia.
Conclusions. Structural changes in the cardiovascular system in patients with CGN develop in the predialysis period of the disease and the most common variants of defeat are coronary heart disease, arrhythmias and heart failure. The existence of anemia with cardiovascular complications in CGN is associated with deterioration of renal nitrogen-excretive function.

Links to authors:
I.T. Murkamilov¹, R.R. Kaliev¹, K.R. Kaliev², K.A. Aitbaev²
1 Kyrgyz State Medical Academy named after I.K. Akhunbaev (92 Akhunbaev St. Bishkek 720020 Kyrgyz Republic),
2 National Center of Cardiology and Internal Medicine named after academician Mirsaid Mirrakhimov (3 Togolok Moldo St. Bishkek 720040 Kyrgyz Republic)


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