Home

Influence of patrinia scabiosifolia on the resistence of mice to whole-body vibration

Written by Khasina E.I., Moiseenko L.I.

  UDK: 612.014.45/.015.46:582.971.3 DOI: 10.17238/PmJ1609-1175.2016.3.58–61 | Pages: 58–61 | Full text PDF | Open PDF 

Annotation:

Objective. Patrinia scabiosifolia Fisch. ex Link (fam. Valerianaceae) is commonly used for treatment of insomnia and anxiety. Efficiency of tincture of P. scabiosifolia for correction of psychosomatic damages induced whole-body vibration in male CD-1 mice was studied. Methods. The effect of supplementing P. scabiosifolia preparation were investigated on stress response in mice during shuttle or transportation vibration simulation. Results. Intragastric introduction of tincture P. scabiosifolia at a dose 5 ml/kg has increased duration of physical work until absolute fatigue and optimized behavior activity in the mice. Patrinia exhibited energy-saving effect in liver and skeletal muscles and normalized hormonal status of mice under whole-body vibration. Conclusions. The present research revealed that the application of P. scabiosifolia root tincture will be effective in suppressing vibration stress responses and can be recommended as vibroprotective remedy.

Links to authors:

E.I. Khasina, L.I. Moiseenko
V.L. Komarov Gornotayozhnaya Station FEB RAS (26 Solnechnaya St. Gornotayozhnoye vlg, Ussuriysk district, Primorye territory, 690033 Russian Federation)


1. Babanov S.A., Vakurova N.V., Azovskova T.A. Vibration white finger. Diagnostic and therapeutic measures. Samara: Ofort, 2012. 160 p.
2. Vorobyeva V.V., Shabanov P.D. Vibration amd anti vibration tools [Pharmacology of extreme conditions: in 12 volumes / edited by P.D. Shabanov]. StP.: Inform-navigator, 2015. Vol. 6. 416 p.
3. Zorikova O.G., Khasina E.I. Patrinia scabiosaefolia. Vladivostok: Dalnauka, 2005. 111 p.
4. Mazina N.K., Vorobyeva V.V., Alekseeva O.A., Babin A.P. Influence of energy exchange regulators on physical endurance of rats at general vibration (experimental study) // Medical Newsletter of Vyatka. 2004. No. 1. P. 11–13.
5. Pankov V.A., Kuleshova M.V., Katamanova E.V., Kartapeltseva N.V. Effect of vibration on the functional activity of the nervous system in experiments with animals // Bulletin of the East Siberian Scientific Center SB RAMS. 2013. No. 3, Part. 2. P. 113–118.
6. The technology of medicinal forms / edited by L.A. Ivanova. М.: Meditsina, 1991. Vol. 2. P. 364–365.
7. Ubeeva I.P., Tsybikova E.N., Razuvaeva Ya.G. [et al.]. Phytocorrection of nervous system diseases (review) // Bulletin of Buryat State University. 2013. No. 12. P. 7–10.
8. Ushkalova A.V., Illarionova T.S. Efficacy and safety of herbal antidepressants and sedative medicines // Pharmateca. 2007. No. 20. P. 10–14.
9. Khasina E.I. Correction stress response of mice to intense noise action with Patrinia scabiosaefolia // Proceedings of the Samara Scientific Center of the Russian Academy of Sciences. 2013. Vol. 15, No. 3. P. 1980–1983.
10. Yanshina E.N., Lyubchenko P.N. Psychoemotional violations in vibration disease // Occupational Medicine and Industrial Ecology. 2001. No. 2. P. 32–35.
11. Panossian A., Wikman G. Effect of adaptogens on central nervous system // Arquiv. Brasil. Fitomed. Cientifica. 2005. Vol. 3, No. 1. P. 29–51.
12. Рrisby R.D., Lafage-Proust M., Malaval L. [еt al.]. Effect of whole body vibration on the skeleton and other organ systems in man and animal models: what we know and what we need to know // Ageing Res. Rev. 2008. No. 7. P. 319–329.
13. Ronchese F., Bovenzi M. Occupational risk and health disorders in transport drivers // G. Ital. Med. Lav. Ergon. 2012. Vol. 34, No. 3. P. 352–359.
14. Toshima H., Endo Y. Effect of whole-body vibration on autonomic nervous system // Autonom. Neurosci. Basic Clin. 2006. Vol. 130, No. 1. P. 65–68.
15. Zou W., Wen X., Zheng Y. [et al.]. Metabolic study on preventive effect of Patrinia scabiosaefolia Fisch. on multipathogen induced pelvic inflammatory disease in rats // Evidence-based Complem. Altern. Med. 2015; 2015/170792.

PUBLISHER: "MEDITSYNA DV"

Founded in 1997  |  Editions in a year: 4, Articles in one issue: 30 |  ISSN of print version: 1609-1175  |  Ind.: 18410 (Agency "Rospechat’")  |  Edition: 1000 c.