Influence of patrinia scabiosifolia on the resistence of mice to whole-body vibration

Written by Khasina E.I., Moiseenko L.I.

  UDK: 612.014.45/.015.46:582.971.3 DOI: 10.17238/PmJ1609-1175.2016.3.58–61 | Pages: 58–61 | Full text PDF | Open PDF 


Objective. Patrinia scabiosifolia Fisch. ex Link (fam. Valerianaceae) is commonly used for treatment of insomnia and anxiety. Efficiency of tincture of P. scabiosifolia for correction of psychosomatic damages induced whole-body vibration in male CD-1 mice was studied. Methods. The effect of supplementing P. scabiosifolia preparation were investigated on stress response in mice during shuttle or transportation vibration simulation. Results. Intragastric introduction of tincture P. scabiosifolia at a dose 5 ml/kg has increased duration of physical work until absolute fatigue and optimized behavior activity in the mice. Patrinia exhibited energy-saving effect in liver and skeletal muscles and normalized hormonal status of mice under whole-body vibration. Conclusions. The present research revealed that the application of P. scabiosifolia root tincture will be effective in suppressing vibration stress responses and can be recommended as vibroprotective remedy.

Links to authors:

E.I. Khasina, L.I. Moiseenko
V.L. Komarov Gornotayozhnaya Station FEB RAS (26 Solnechnaya St. Gornotayozhnoye vlg, Ussuriysk district, Primorye territory, 690033 Russian Federation)

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