The impact of glyprolines on processes of ulceration in the experiment

Written by Tolstenok I.V., Fleyshman M.Yu., Slobodenyuk E.V.

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A wide range of biological activity of regulatory peptides of glyproline family allows us to consider them promising pharmacological agents. We detected the ability of peptides of glyproline range to show an anti-ulcer activity. Tripeptide proglyprol exhibits it in a greater degree which suggests the possibility of creating on its basis a new drug. The paper discusses the general idea of the regulatory peptides, there are some published data about the effect of the peptides of glyproline family and peptide semax on the ulcer formation processes and summarizes the possible mechanisms of oligopeptides action.

Links to authors:

I.V. Tolstenok, M.Yu. Fleyshman, E.V. Slobodenyuk
Far Eastern State Medical University (35 Muraveva-Amurskogo St. Khabarovsk 680000 Russian Federation)

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