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Trophic factors of bone growth, their morphogenetic characterization and clinical significance

Written by Kostiv R.E., Kalinichenko S.G., Matveeva N.Yu.

  UDK: 611.018.4:612.753:616.7(048.8) | Pages: 10–16 | Full text PDF | Open PDF 

Annotation:
The literature review dedicated to regeneration mechanisms of bone tissue. Summarized the data on topochemistry and functions of morphogenetic and growth factors, their participation in the regulation of the regenerative processes on different levels of the fracture union. Given the detailed critical overview of the technologies of production and clinical use of morphogenetic proteins on the basis of recombinant technologies of gene engineering with reparative osseogenesis. One of the most promising ways of increasing the osteoinductive properties of biomaterials and bone tissue regeneration control process is the creation of various composites having osteoinductive and osteoconductive properties, containing growth factors, and at the same time performing the role of the osteogenic matrix.

Links to authors:

R.E. Kostiv, S.G. Kalinichenko, N.Yu. Matveeva
Pacific State Medical University (2 Ostryakova Ave. Vladivostok 6900950 Russian Federation)


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PUBLISHER: "MEDITSYNA DV"

Founded in 1997  |  Editions in a year: 4, Articles in one issue: 30 |  ISSN of print version: 1609-1175  |  Ind.: 18410 (Agency "Rospechat’")  |  Edition: 1000 c.