Sudden cardiac death and morphofunctional diagnostics previous age neurotrophic changes of organisms

Written by Shvalev V.N., Rogoza F.N., Tarsky N.A., Sergienko V.B., Ansheles A.A., Reutov V.P., Yudaev A.A.

  UDK: 616.12-036.886-02:616.12-06:616.8-073.584 | Pages: 42–51 | Full text PDF | Open PDF 


Presented the results of morphological and functional studies of the pathogenesis mechanisms of sudden cardiac death (SCD). Proved the hypothesis that susceptibility to SCD determined by the degree denervation changes in the cardiovascular system. The risk of SCD increases in conjunction with the progression of coronary heart disease and the presence of prior changes in the central nervous system and neurodystrophic processes in a body. Functional sympathectomy of the cardiovascular system is the result of age-related involution changes the sympathetic division of the autonomic nervous system in conjunction with a partial deafferentation heart. The method of spectral analysis shows that the sharp decrease in sympathetic activity that is fraught with the SCD, is much faster in hypertensive patients. The likelihood of sudden death associated with social stress and emotional status of the organism, and it is increased in the presence of bad habits and depressive states.

Links to authors:
V.N. Shvalev1, F.N. Rogoza1, N.A. Tarsky2, V.B. Sergienko1, A.A. Ansheles1, V.P. Reutov3, A.A. Yudaev4
1 A.L. Myasnikov Institute of Clinical Cardiology of Russian Cardiology Research and Production Complex (15a 3th Cherepkovskaya St. Moscow 121552 Russian Federation),
2 International University of Nature, Society and Man (19 Universitetskaya St. Dubna 41980 Russian Federation),
3 Institute of Higher Nervous Activity and Neurophysiology of RAS (5a Butlerova St. Moscow 117485 Russian Federation),
4 Moscow Technological University (78 Vernardskogo St. Moscow 119454 Russian Federation)

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