Clinical course of the early postoperative period of phacoemulsification on the background of various schemes of antibacterial prophylaxis

Written by Fedyashev G.A., Eliseeva E.V.

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Objective. The objective of the study is to analyze the effect of various types of antibacterial prophylaxis (local and systemic) on the severity of postoperative reactive inflammation in the early period after phacoemulsification. Methods. 185 patients – 246 eyes with age-related cataract – divided into two equal groups. Representatives of the 1st group (123 eyes) received instillations of levofloxacin within 3 days before the operation, representatives of the 2nd group (123 eyes) additionally – levofloxacin inside 500 mg once a day, starting the day before the intervention, for five days. The signs of reactive inflammation were evaluated according to the S.N. Fedorov and E.V. Yegorova classification at the 1, 3 and 10 days after the operation.  Results. On the 1st and 3rd day after the surgery, significantly better results on the response from the moisture of the anterior chamber of the eye were noted among the patients of the 2nd group. On the 10th day, there were no significant differences between the groups. Conclusions. We can talk about a significant decrease in the severity of the reactive inflammatory process from the anterior chamber of the eye after phacoemulsification with systemic antibacterial prophylaxis with fluoroquinolones.

Links to authors:

G.A. Fedyashev1, 2, E.V. Eliseeva1
1 Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690950 Russian Federation),
2 Primorskiy Centre of Eye Microsurgery (100e Borisenko St. Vladivostok 690088 Russian Federation)

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