Regularities of changes in brain bioelectric activity in case of age-related macular degeneration

Written by Pestryakova Ya.F., Rybchenko A.A., Shabanov G.A., Zaporozhets T.S.

  UDK: 617.751.6-02:617.735-073.584 | Pages: 26–29 | Full text PDF | Open PDF 


Objective. The objective of the study is to analyze the bioelectrical activity of the brain in the early stages of age-related macular degeneration.  Methods. We studied the deviations in the bioelectrical activity of the brain in the early stages of age-related macular degeneration of the retina in 10 patients aged 60–77 (control – 10 practically healthy people). The analysis was performed with the help of the RS MEGI-01 developed in the laboratory of environmental neurocybernetics of the Research Center ‘Arktika’ FEB RAS. The obtained data were subjected to a software-hardware analysis and represented in the form of a spectral matrix and spectrum envelope graphs displaying the spectral estimation in different frequency ranges corresponding to a certain group of vegetative receptors.  Results. In patients with macular degeneration of the retina detected the regularities in the characteristics of the spectral matrix on qualitative and quantitative characteristics. For the pathological state were received the spectral estimates for the sum of the spectral matrices. Significant differences in the frequency ranges reflecting the state of the vegetative receptors of the eye were revealed.  Conclusions. Objectively confirmed data from clinical trials have proved the advisability of using diagnostics by studying the bioelectrical activity of the brain in patients with age-related macular degeneration. Criteria for screening diagnostics of this disease have been developed with the help of examination on the RS-MEGI-01.

Links to authors:
Ya.F. Pestryakova1, A.A. Rybchenko2, G.A. Shabanov2,
T.S. Zaporozhets3
1 Medical Association FEB RAS (95, Kirova st., Vladivostok, 690022 Russian Federation),
2 Research Centre ‘Arktika’ MA FEB RAS (95, Kirova st., Vladivostok, 690022 Russian Federation),
3 Research Institute of Epidemiology and Microbiology named after G.P. Somov (1, Selskaya st., Vladivostok, 690087 Russian Federation)

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