Interleukin-17 family in atopy and allergic diseases

Written by Prosekova E.V., Turyanskaya A.I., Dolgopolov M.S.

  UDK: 616–056.43–092–056.7:612.017.1 | Pages: 15–20 | Full text PDF | Open PDF 


The review provides the information about the features of molecular and genetic mechanisms and biological effects of Interleukin-17 family members in immunopathogenesis of atopy and design of allergic pathology. The correlation of Interleukin- 17 family members in the system of cytokine initial regulation, development and course of allergic diseases was analyzed. The significance of genetic predictors and imbalance of cytokine profile of Interleukin-17 family is discussed to foresee the design of endo- and phenotypic features of the course of bronchial asthma, allergic rhinitis, and atopic dermatitis.

Links to authors:

E.V. Prosekova, A.I. Turyanskaya, M.S. Dolgopolov
Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690002 Russian Federation)

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