Molecular epidemiological evaluation of the impact of globalization processes on the formation of populations of Salmonella Typhimurium in Primorie and other regions of Siberia and the Far East

Written by Kuznetsova A.A., Shubin F.N., Rakov A.V., Yakovlev A.A.

  UDK: 616.98:579.842.14–036.22(571.6+571.1/5) | Pages: 47–53 | Full text PDF | Open PDF 


Objective. Because of product imports from different countries there is a pronounced migration of serotypes of salmonella into Russia, and there is a risk of import of more highly-virulent and antibiotic-resistant microorganisms with contaminated products.
Methods. We have studied 457 strains of Salmonella Typhimurium, isolated from sick people, and 29 strains separated from food products samples in Siberia and Russian Far East. We have analyzed the plasmid features of 486 strains obtained from different ecological origins; sensitivity to antibiotics was studied by discdiffusion method on Müller–Hinton agar in 102 of them.
Results. It was established that population of S. Typhimurium, developed in different regions of Siberia and Russian Far East, is heterogeneous both in plasmid features and in sensitivity to antibiotics. The population is formed because of contaminated products delivery from different regions of Russia and abroad. Generally, imported strains of S. Typhimurium caused focal morbidity; meanwhile strains separated from local meat products caused sporadic morbidity. Strains of S. Typhimurium separated from sick people and livestock products in the region had a similar plasmid type and sensitivity to antibiotics; this is the evidence of their epidemiological relation.
Conclusions. To optimize the system of epidemiological surveillance of salmonellosis caused by S. Typhimurium, it is advisable to examine imported livestock products for the presence of salmonella and sensitivity of separated strains to antibiotics.

Links to authors:

A.A. Kuznetsova1, F.N. Shubin1, A.V. Rakov1, A.A. Yakovlev1, 2
1 Research Institute of Epidemiology and Microbiology named after G.P. Somov (1 Selskaya St. Vladivostok 690087 Russian Federation),
2 Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690002 Russian Federation)

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