Risk factors that contribute to the formation of combined forms of tuberculosis and HIV infection in Primorsky Krai

Written by Kornilov M.S., Yakovlev A.A., Pozdeeva E.S., Zhdanova S.N.

  UDK: 616–002.5–06:616–097–022:578.828–036.22(571.63) | Pages: 87–91 | Full text PDF | Open PDF 


Objective. An epidemiological situation was assessed for the combined forms of tuberculosis and HIV-infection in the Primorsky territory and factors promoting their formation.
Methods. The cards of personal records of patients with tuberculosis combined with HIV-infection (form 263/y-TБ) of Primorskiy Regional Tuberculosis Dispensary for 2003-2017 were analyzed. We used the data of monitoring of the combined forms of HIV infection and tuberculosis of the Primorsky Center for the Prevention and Control of AIDS and Infectious Diseases. During the processing of data, we used common for epidemiology
Results. In the last five years, the epidemiological situation of the combined HIV / TB forms in Primorsky territory has gradually improved against the background of a decrease in the incidence of mono-tuberculosis in the population and the continuing increase in the incidence of HIV-infection. Factors that significantly influence the risk of forming mixed forms of HIV-infection and tuberculosis are: male sex, age, socially maladaptive population, the presence of co-morbidities, drug abuse, uncontrolled sexual behavior and alcohol abuse.
Conclusions. Unfortunately, the current epidemiological surveillance system does not take into account the factors that currently determine the epidemiological features of tuberculosis and HIV-infection, as well as the risks of forming their combined forms. However, as new data on the conditions conducive to the development of the epidemic process appear, information flows need to be expanded to conduct epidemiological analysis and make timely management decisions in the field of preventing co-infected forms of HIV-infection and tuberculosis.

Links to authors:

M.S. Kornilov1, A.A. Yakovlev1, E.S. Pozdeeva1, S.N. Zhdanova2
1 Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690002 Russian Federation), 2 Scientific Сentre for Family Health and Human Reproduction Problems (16 Timiryazeva St. Irkutsk 664003 Russian Federation)

1. Glans S. Medico-biological statistics. Moscow: Practice, 1998. 459 p.
2. Mindlina A.Ya. Epidemiological features the antroponoznsis of infections of various degree of controllability and scientific justification of optimization of supervision at the present stage: Thesis MD. Moscow, 2014. 46 p.
3. Motanova L.N., Grabovskaya M.S., Folts I.V., Skorobach Yu.M. The characteristic of the contingents of patients with a combination of tuberculosis and HIV infection in the territory with a high case rate tuberculosis // Pacific Medical Journal. 2007. No. 4. P. 51–53.
4. Nechaev V.V., Ivanov A.C., Panteleev A.M. Socially important infections. Part 2 (mikst-infections). Saint Petersburg: Beresta, 2011. 312 p.
5. Sevivanov A.A. Infektion of the admixed etiology – accident or ecological pattern // Patterns of epidemic process: Works of Institute of Pasteur. 1983. Vol. 61. P. 47–49.
6. Sotnichenko S.A., Markelova E.V., Sklyar L.F., Yakovlev A.A. HIV infection, combined with tuberculosis in Primorsky Krai: Modern questions of epidemiology, clinic, immunopathogenesis, diagnostics and treatment. Vladivostok: Dalnauka, 2009. 166 p.
7. Supotnisky M.V. Microorganisms, toxins and epidemics. Moscow: Vuzovskaya kniga, 2000. 376 p.
8. Cibikova B., Sabgaida T.P. Epidemiology of tuberculosis, combined with HIV infection // Health Care in the Russian Federation. 2012. No. 6. P. 7–11.
9. Shamanova L.V. Maslauskene T.P. Contribution of various risk factors into tuberculosis incidence // Siberian Medical Journal. 2011. No. 6. P. 28–30.
10. Shkarin V.V., Blagonravova A.C. Epidemiological features of the combined infections. Nizhny Novgorod: Nizhny Novgorod State Medical Academy Publishing House, 2017. 400 p.
11. Yakovlev A.A. Integration epidemiology of hepatitis B and C in Primorsky Krai // Vladivostok: Medicina DV, 2011. 116 p.
12. Yakovlev A.A., Savilov E.D. Problematic issues of the general epidemiology. Novosibirsk: Nauka, 2015. 290 p.
13. Yakovlev A.A., Pozdeeva E.S., Kornilov M.S. [et al.]. Integration approach to studying of a case rate tuberculosis and HIV infection of the population of Primorsky Krai // Tuberculosis and Pulmonary Diseases. 2017. Vol. 95, No. 2. P. 33–39.
14. Yakovlev A.A., Burnasheva L.S., Jdanova S.N. Integration epidemiology of tuberculosis and HIV infection on model of the Sakha (Yakutia) Republic. Vladivostok: Medicina DV, 2017. 112 p.
15. Yakovlev A.A., Kornilov M.S., Jdanova S.N. Dynamics of changes in the structure of circulating genotypes in Primorye Territory M. tuberculosis // Materials of the anniversary scientific and practical conference dedicated to the 95th anniversary of the State Sanitary and Epidemiological Service of Russia. Vladivostok, 2017. P. 100–101.


Founded in 1997  |  Editions in a year: 4, Articles in one issue: 30 |  ISSN of print version: 1609-1175  |  Ind.: 18410 (Agency "Rospechat’")  |  Edition: 1000 c.