Epidemiology of nonspecific periodontitis caused by bacteria Leptotrichia, chronic and recurrent course of infection

Written by Strelnikova N.V., Antonova A.A., Turkutyukov V.B., Shapovalenko E.S.

  UDK: 616.311.2–002-022.7:579.844.13 | Pages: 71–74 | Full text PDF | Open PDF 


Objective. The study objective is to assess the epidemiological significance of bacteria Leptotrichia in the development of purulentseptic infections of an oral cavity.
Methods. We carried out a retrospective epidemiological analysis of microbiocenosis of pathological periodontal pockets in nonspecific periodontitis in 432 patients aged over 20 y.o.
Results. Microbiocenosis of pathological periodontal pockets in chronic and recurrent of medium and severe periodontitis more pronounced species diversity as compared to microbiocenosis in acute low periodontitis. Bacteria Leptotrichia were detected in all observations typically in association with Staphylococcus aureus and Streptococcus pyogenes, supporting the chronic recurrent process.
Conclusions. Analysis results of microbial status of periodontal pockets in patients with chronic periodontitis enable to recommend the use of empiric treatment of this pathology with antibacterial chemotherapeutic agents affecting non-spore-forming anaerobic bacteria.

Links to authors:

N.V. Strelnikova1, 2, A.A. Antonova1, V.B. Turkutyukov3, E.S. Shapovalenko1
1 Far Eastern State Medical University (35 Muravyeva-Amurskogo St. Khabarovsk 680000 Russian Federation),
2 Regional Clinic Hospital No. 1 (9 Krasnodarskaya St. Khabarovsk 680000 Russian Federation),
3 Pacific State Medical University (2 Ostryakova Ave. Vladivostok 690002 Russian Federation)

1. Antonova A.A. Dental caries in children under microelementoses of the Khabarovsk Territory: Thesis MD. Omsk. 2006. 350 p.
2. Vinogradova A.V., Kalk E.A., Molokov V.D. New approaches in the treatment of patients with chronic periodontitis with the use of bone tissue revascularization. Irkutsk: ISCST. 2017. 123 p.
3. Zelenova E.G. Microflora of oral cavity: norm and pathology: A study guide. Nizhny Novgorod: NSMA Publishing House. 2004. 158 p.
4. Kovalevsky A.M., Kovalevsky V.A. Etiology and pathogenesis of inflammatory periodontal diseases (review of literature) // Institute of Dentistry. 2017. No. 4. P. 88–90.
5. Kuzmina E.M., Kuzmina I.N., Petrina E.S. Stomatological incidence of the Russian population. Condition of periodontal tissues and oral mucosa / ed. by O.O. Yanushevich. Moscow: MSMSU. 2009. 236 p.
6. Lebedev D.V. Microbiocenosis of the oral cavity in patients with generalized periodontitis, a method of diagnosis and correction: Thesis PhD. Moscow, 2011. 18 p.
7. Leus P.A. Preventive communal stomatology. Moscow: Meditsinskaya Kniga, 2008. 444 p.
8. Sgibneva V.A. The assessment prevalence and intensity of the periodontal diseases in the adult population on Barnaul // Health and Education Millenium. 2016. Vol. 18, No. 5. P. 57–60.
9. Strelnikova N.V., Koltsov I.P. Antonova A.A. [et al.]. Method of cultivation of bacteria of the genus Leptotrichia – residents of the oral cavity microflora // Patent of the Russian Federation 2441908. 2012. Bul. 4.
10. Strelnikova N.V. Microbiological properties of potential pathogens of the genus Leptotrichia: Thesis PhD. Vladivostok, 2010. 218 p.
11. Changes in the incidence of periodontal pathogens during longterm monitoring and after application of antibacterial drugs // Folia Microbiol. 2009. Vol. 54, No. 5. P. 429–435.
12. Chappie I.L.C. Periodontal diagnosis and treatment where does the future lie? // Periodontology 2000. 2009. Vol. 51, No. 1. P. 9–24.
13. Higashi Y. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients // Hypertension. 2008. Vol. 51, No. 2. P. 446–453.
14. Kriebel K., Hieke C., Müller-Hilke B. [et al.]. Oral biofilms from symbiotic to pathogenic interactions and associated disease – connection of periodontitis and rheumatic arthritis by peptidylarginine deiminase // Front Microbiol. 2018. doi: 10.3389/ fmicb.2018.00053.
15. Timmerman M.F., van der Weijden G.A. Risk factors for periodontitis // Int. J. Dent. Hyg. 2016. Vol. 4, No. l. P. 2–7.


Founded in 1997  |  Editions in a year: 4, Articles in one issue: 30 |  ISSN of print version: 1609-1175  |  Ind.: 18410 (Agency "Rospechat’")  |  Edition: 1000 c.