Opportunities for the treatment of cognitive-emotional disorders in patients with chronic ischemia of the brain

Written by Shuteeva T.V.

  UDK: 616.831-005.4-06:616.89-008.454-085.214.2 | DOI: 10.17238/PmJ1609-1175.2019.1.70–73  Pages: 70–73 | Full text PDF | Open PDF 


Objective: The objective is to assess the possibility of the usage of medications of citicoline range (neipilet) to reduce cognitive and obsessive-compulsive in patients with chronic brain ischemia.
Methods: The study was performed on two groups of patients with chronic cerebral ischemia: the main and control patients aged 54 to 75 years. In the presence of somatic pathology, patients of the two groups matched each other. Patients of the main group received Neupilept orally at 1000 mg per day for 30 days in combination with antiplatelet and vascular agents. The control group received only traditional therapy with the above groups of drugs. The neurocognitive status was assessed using the Schulte test and the MoCA scale. The effectiveness of the treatment of anxiety and depressive disorders was determined on the scales of depression and anxiety Hamilton (HDRS and HARS).
Results: Patients who received Neupilept showed improved attention, accelerated thinking, Neupilept showed a positive effect on mental and somatic anxiety. Patients in the control group did not subjectively indicate improved cognitive functions, objective testing also showed no significant positive
Conclusions: The study on scales and questionnaires, which determines the level of positive dynamics of cognitive functions (Schulte's test, MoSA-test), anxiety and depression (HARS and НDRS) indicates a positive therapeutic effect of Neupilept. The use of Neupilept for the correction of the clinical picture of chronic cerebral ischemia improves the quality of life of patients, contributes to the activation of cognitive functions and normalizes psycho-emotional disorders.

Links to authors:

T.V. Shuteeva
Kursk State Medical University (3 Karla Marksa St. Kursk 305041 Russian Federation)

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