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Risk factors for retinopathy of prematurity at different stages of gestation

Written by Krasnogorskaya V.N., Gusev A.N., Syromukova A.S.

  UDK: 616.735–007.281:617.723–053.32 | DOI: 10.17238/PmJ1609-1175.2019.2.11–14 | Pages: 11–14 | Full text PDF | Open PDF 

Annotation:

Objective: Study objective is to determine the prevalence of retinopathy of prematurity that required a neonatal resuscitation, and is to assess the impact of some risk factors with the use of modern perinatal technologies of breathing support and further developmental care in Amur Region.
Methods: We examined two matched infants groups with a gestational age at birth 34 weeks and/or body weight 2,250 gr or less: 102 infants with retinopathy of prematurity (1st group) and 125 infants without retinopathy of prematurity (2nd group).
Results: Depending on the gestational age the prevalence of retinopathy of prematurity distributed as follows: among infants born until the 28th week of pregnancy – 77.4 %, until the 30th week – 48.5 %, until 32nd week – 31.2 %. Depending on body weight at birth the prevalence of retinopathy of prematurity was: less than 1,000 gr – 55.8 %, less than 1,250 gr – 52.7 %, less than 1,500 gr – 40.3 %, less than 1,750 gr – 30.9 %, less than 2,000 gr – 24.1 %.
Conclusions: The prevalence of retinopathy of prematurity is 17.8 % of the total number of infants born until the 34 weeks of gestational age and body weight at birth less than 2,000 gr in Amur Region. Birth asphyxia can be considered to be the most significant intranatal risk factor for retinopathy of prematurity. Reduction of the first rate according to Apgar scale up to 4 scores and less in infants with very low and extremely low body weight does not only increase the frequency of development of severe perinatal injury of the central nervous system but also is associated with retinopathy of prematurity.

Links to authors:

V.N. Krasnogorskaya, A.N. Gusev, A.S. Syromukova
Amur State Medical Academy (95 Gorkogo St. Blagoveschensk 675013 Russian Federation)


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