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Amygdalin in kernels of stone fruits of Rosaceae family growing in Primorye

Written by Manyakhin A.Yu., Koldaev V.M.

  UDK: 615.322:582.711.71:612.396.175(571.63) | DOI: 10.17238/PmJ1609-1175.2019.2.62–64 | Pages: 62–64 | Full text PDF | Open PDF 

Annotation:

Objective: comparative determination of glycoside of amygdalin in kernels of stone fruits of Rosaceae family growing in southern districts of Primorskiy territory.
Methods: We used fruits of Prunus padus and Prunus maackii, apricots, plums and cherries of different species, and we used their kernels to make an extract with 95 % ethanol using simple maceration. We performed spectrophotometry, liquid chromatography and mass-spectroscopy to examine extracts.
Results: Due to combination of physical and chemical parameters amygdaline was identified in extracts of kernels of bird cherry fruits. Its highest content was detected in kernels of Prunus maackii fruits. Intervarietal differences of glycoside content over the species range were insignificant. The content of amygdalin in kernels of Prunus maackii was 16–18 % lower than in bitter almonds, however kernels of this bird cherry fruits have much less ballast substances that simplifies manufacturing technology.
Conclusions: Kernels of Prunus maackii fruits are similar to bitter almond in amygdalin content and are show promise as raw materials resource to produce herbal medicinal products of amygdalin.

Links to authors:

A.Yu. Manyakhin1, 2, V.M. Koldaev1
1 Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences (159 100-letiya Vladivostoku Ave. Vladivostok 690022 Russian Federation),
2 Vladivostok State University of Economics and Service (41 Gogolya St. Vladivostok 690014 Russian Federation)


1. Ablaev N.R., Majmanova A.M. Molecular and Biochemical Aspects of Vitamin B17 // Bulletin of the Alma-Ata State Institute of Advanced Medical Education. 2013. No. 4. P. 71–73.
2. Amygdalin. URL: https:/ru.wikipedia.org/wiki/Amygdalin (date of access: 7.02.2019).
3. Koldaev V.M. Numerical indexes of absorption spectra of extracts from leaves of Primorye plants. Vladivostok: Dalnauka, 2018. 120 p.
4. Minina S.A., Kaukhova I.E. Chemistry and technology of phytopreparations. Moscow: GEOTAR-Media, 2009. 500 p.
5. Myatlev V.D., Panchenko L.A., Riznichenko G.Y. [et al.]. Theory of probability and mathematical statistics. Mathematical models. Moscow: Academia, 2009. 320 p.
6. Properties and application of bitter almonds. URL: http://orehiplus. ru/mindal/svojstva-i-primenenie-gorkogo-mindalya.html (date of access: 7.02.2019).
7. Berenguer-Navarro V., Giner-Galvan R.M., Grane-Teruel N. Chromatographic determination of cyanoglycosides Prunasin and Amygdalin in plant extracts using a porous graphitic carbon column // J. Agric. Food Chem. 2002. Vol. 59, No 24. P. 6960–6963.
8. Blaheta R.A., Nelson K., Haferkamp A. [et al.]. Amygdalin, quackery or cure? // Phytomedicine. 2016. Vol. 23, No 4. P. 367–376.
9. Bolarinwa I.F., Orfila C., Morgan M.R.A. Amygdalin content of seeds, kernels and food products commercially-available in the UK // Food Chemistry. 2014. Vol. 152. P. 133–139.
10. Cairns T., Siegmund E.G., Chemical ionization mass spectrometry of amygdalin with ammonia gas // Biological Mass Spectrometry. 1982. Vol. 9, No. 7. P. 307–309.
11. Ge B. Y., Chen H. X., Han F. M. [et al.]. Identification of amygdalin and its major metabolites in rat urine by LC–MS/MS // Journal of Chromatography B. 2007. Vol. 857, No. 2. P. 281–286.
12. Lee J., Zhang G., Wood E. [et al.] .Quantification of Amygdalin in Nonbitter, Semibitter, and Bitter Almonds (Prunus dulcis) by UHPLC-(ESI)QqQ MS/MS // Journal of Agricultural and Food Chemistry. 2013. Vol. 61, No. 32. P. 7754–7759.
13. Makarevic J., Tsaur I., Juengel E. [et al.]. Amygdalin delays cell cycle progression and blocs growth of prostate cells in vitro // Life Sciences. 2016. Vol. 147. P. 137–142.
14. Qian L., Xie B., Wang Y. [et al.]. Amygdalin mediated inhibition of non-small sell lung cancer cell invasion in vitro // IJCEP. 2015. Vol. 8, No. 5. P. 5363–5370.

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Founded in 1997  |  Editions in a year: 4, Articles in one issue: 30 |  ISSN of print version: 1609-1175  |  Ind.: 18410 (Agency "Rospechat’")  |  Edition: 1000 c.