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Стволовые клетки нейронального происхождения в мозге млекопитающих

23 Март 2011
Автор: Охотин В.Е., Ревищин А.В., Павлова Г.В.

  Индекс УДК: 611.018.82:576.3 | Страницы: 60–65 | Полный текстСкачать PDF 

Аннотация:

В последние 15 лет получены новые знания о стволовых клетках, позволяющие по‑новому понять функционирование нервной ткани в норме и патологии. Показано, что пролиферирующие стволовые клетки в дефинитивном мозге при определенных условиях могут участвовать в репаративной регенерации, замещая погибшие элементы. Установлены геномные механизмы управления пролиферацией и дифференцировкой стволовых клеток. Показано их участие в генезе злокачественных опухолей и тропизм этих клеток к опухолям. Данные факты открывают новые направления в исследовании функционирования и развития мозга. Нейтральные стволовые клетки могут быть использованы для создания новых технологий, лечения нейродегенеративных и онкологических заболеваний мозга.

Ссылки на авторов:

Ревищин А.В.
Канд. биол. наук, старший научный сотрудник лаборатории сравнительной нейробиологии позвоночных ИПЭЭ РАН; e‑mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.
В.Е. Охотин, Г.В. Павлова

Институт биологии гена РАН (119334 г. Москва, ул. Вавилова, 34/5),
А.В. Ревищин
Институт проблем экологии и эволюции им. А.Н. Северцова РАН (119071 г. Москва, Ленинский пр‑т, 33)

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ИЗДАТЕЛЬСТВО: Медицина ДВ

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